Sylvie Rusakiewicz

Biography

I am a project leader at the H-TIDE facility of the Lausanne Branch of the Ludwig Institute for Cancer Research. My laboratory here is working to develop a high throughput method to assess the best immune modulatory combination capable of activating, reprogramming and expanding tumor-specific T cells for personalized immunotherapies. I obtained my master’s degree in Biology from Nottingham Trent University in 2000, and started my Ph.D. training at the Anthony Nolan Research Institute/University College of London with Prof. Alejandro Madrigal and Prof. Paul Travers, working on strategies to develop a bcr/abl-derived peptide vaccine for chronic myelogenous leukemia using dendritic cells and artificial antigen presenting cells. I then joined Prof. Jeffrey Molldrem laboratory at the MD Anderson Cancer Center to generate transgenic T cells specific to another leukemia associated antigen, proteinase 3, with optimal TCR avidity for recognition and killing of tumor cells.

Research Interest

Cancer biology, immunetherapy, diagnostics and vaccine development