Andrea Rinaldi
Research associate
Genomics Facility
Oncology Institute of Southern Switzerland
Switzerland
Biography
May 2003- present Senior biologist at the Oncology Institute of Southern Switzerland, Bellinzona, Switzerland. September 2002 - May 2003 Visiting Scientist at the Dept. of Haematology, Barts and The London School of Medicine, London, UK. May 2000 - May 2003 Research Fellowship from the “Città della Speranza” Foundation , laboratory for Pediatric Oncohaematology, Pediatrics Department, University of Padova, Padova Italy. September 1999 - May 2000. Graduate Researcher at the Haematology Clinic, Clinica Pediatrica, University Hospital of Bari, Bari, Italy. 1999 Research Fellowship, Ministero della Sanità : intra-hospital ISDN Videonetwork for the study and care of congenital cardiopathies (ex art. 12 comma 2, lett. B del DLGS 502/92 Regione Puglia, Italy). 1998 Research Fellowship: Istituto Superiore di Sanità n.93/G/T66 with the project: “Mother-child health risks prevention factors”. Objectives: infection risk assessment at the UTIN (Unità Terapie Intensive Neonatali; newborn intensive therapy unit of the Azienda University Hospital of Foggia, Foggia, Italy). 1994-1999. Graduate student at the Immunology and cell biology laboratory Clinica Pediatrica. Bologna
Research Interest
My primary research interest consists in identification of novel genes as a possible therapeutic targets in lymphomas. I’m currently working with the Affymetrix GeneChip to perform global transcript analysis and genome-wide DNA profiling. In particular, I am studying the role of Syk tyrosine kinase in lymphomas. At the present time I’m involved in understanding differences in gene expression in clinical trials
Publications
-
Rinaldi A, Poretti G, Kwee I, Zucca E, Catapano CV, Tibiletti MG, Bertoni F. Concomitant MYC and microRNA cluster miR-17-92 (C13orf25) amplification in human mantle cell lymphoma. Leukemia & lymphoma. 2007 Jan 1;48(2):410-2.
-
Rinaldi A, Mian M, Chigrinova E, Arcaini L, Bhagat G, Novak U, Rancoita PM, De Campos CP, Forconi F, Gascoyne RD, Facchetti F. Genome-wide DNA profiling of marginal zone lymphomas identifies subtype-specific lesions with an impact on the clinical outcome. Blood. 2011 Feb 3;117(5):1595-604.
-
Rinaldi A, Kwee I, Taborelli M, Largo C, Uccella S, Martin V, Poretti G, Gaidano G, Calabrese G, Martinelli G, Baldini L. Genomic and expression profiling identifies the Bâ€cell associated tyrosine kinase Syk as a possible therapeutic target in mantle cell lymphoma. British journal of haematology. 2006 Feb 1;132(3):303-16.
