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Henry Markram

Professor
School of Life Science
Swiss Institute for Experimental Cancer Research
Switzerland

Biography

Henry Markram started a dual scientific and medical career at the University of Cape Town, in South Africa. He moved to Israel in 1988 and obtained his PhD at the Weizmann Institute.He carried out a first postdoctoral study as a Fulbright Scholar at the NIH, on the biophysics of ion channels on synaptic vesicles using sub-fractionation methods to isolate synaptic vesicles and patch-clamp recordings to characterize the ion channels. He received a tenure track position at the Weizmann Institute where he continued the reverse engineering studies and also discovered a number of core principles of the structural and functional organization such as differential signaling onto different neurons, models of dynamic synapses with Misha Tsodyks, the computational functions of dynamic synapses, and how GABAergic neurons map onto interneurons and pyramidal neurons.

Research Interest

Biophysics

Publications

  • J. Coggan, D. Keller, C. Cal, H. Lehvaslaiho and F. Schurmann et al. Modeling the metabolic response of astrocytes to neuronal activity. 13th European Meeting on Glial Cells in Health and Disease, Edinburgh, SCOTLAND, 2017.

  • Reimann MW, Horlemann AL, Ramaswamy S, Muller EB, Markram H(2017) Morphological Diversity Strongly Constrains Synaptic Connectivity and Plasticity. Cerebral Cortex 27: 4570-4585.

  • Wybo WAM, Markram H, Gewaltig MO (2017) Using the Green's function to simplify and understand dendrites. EPFL, Lausanne.

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