Hilal Lashuel
Associate Professor
School of Life Science
Swiss Institute for Experimental Cancer Research
Switzerland
Biography
Dr. Hilal A. Lashuel received his B.Sc. degree in chemistry from the City University of New York in 1994 and completed his doctoral studies at Texas A&M University and the Scripps Research Institute in 2000. After obtaining his doctoral degree, he became a research fellow at the Picower Institute for Medical Research in Long Island New York. In 2001, he moved to Harvard Medical School and the Brigham and Women's Hospital as a research fellow in the Center for Neurologic Diseases and was later promoted to an instructor in neurology at Harvard Medical School. During his tenure (2001-2004) at Harvard Medical School his work focused on understanding the mechanisms of protein misfolding and fibrillogenesis and the role of these processes in the pathogenesis of Parkinson's and Alzheimer's disease. In 2005 Dr. Lashuel moved Switzerland to join the Brain Mind Institute at the Swiss Federal Institute of Technology Lausanne as a tenure-track assistant professor in neurosciences. Currently, Dr. Lashuel is an associate professor of life sciences and the director of the laboratory of molecular and chemical biology of neurodegeneration. (http://lashuel-lab.epfl.ch/).
Research Interest
To elucidate the molecular mechanisms underlying neurodegeneration in Alzheimer's , Parkinson's and Huntington's disease and develop novel strategies to facilitate the diagnosis, prevention and treatment of these diseases.
Publications
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Ait Bouziad N, Lashuel H (2017) Sequence and structural determinants of Tau aggregation and seeding capacity: Implications for Neurofibrillary Tangle formation and Tau toxicity in Alzheimer's disease.
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Ruggeri F, Mahul AL, Kasas S, Lashuel H, Longo G et al. (2107) Amyloid Single Cell Cytotoxicity Assays by Nanomotion Detection. Cell Death Discovery 3:17053-17060.
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Gopaldass N, Fauvet B, Lashuel H, Roux A, Mayer A (2017). Membrane scission driven by the PROPPIN Atg18. Embo Journal.
