Gfeller David
Assistant Professor in Prerequisite Qualification
Faculty of Biology and Medicine
Universite de Lausanne
Switzerland
Biography
David Gfeller was trained as a physicist and mathematicians. He obtained his PhD in Theoretical Physics at the Swiss Federal Institute of Technology (EPFL) in 2007, working with Prof. Paolo De Los Rios. He then decided to move to Computational Biology and joined the lab of Prof. Gary Bader at University of Toronto where he worked as a post-doc from 2008 to 2010.
Research Interest
Our main research interests lie in the field of computational and systems biology and its applications to cancer and immunology research. Combining large-scale data analysis from genomics and proteomics together with modeling approaches, we aim at better understanding how immunogenicity is regulated in cancer and how cancer cells manage to escape immune recognition despite the presence of cancer specific genetic variants.
Publications
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The pathogen-related yeast protein Pry1, a member of the CAP protein superfamily, is a fatty acid-binding protein. Darwiche R., Mène-Saffrané L., Gfeller D., Asojo O.A., Schneiter R., et al., (2017). 8304-8314.
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Identification of innate lymphoid cells in single-cell RNA-Seq data. Suffiotti M., Carmona S.J., Jandus C., Gfeller D., (2017). 439-450.
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ILC2-modulated T cell-to-MDSC balance is associated with bladder cancer recurrence. Chevalier M.F., Trabanelli S., Racle J., Salomé B., Cesson V., et al., (2017). 2916-2929.