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Biochemistry Experts

Guillaume Philippe

Research Officer
Faculty of Biology and Medicine
Universite de Lausanne
Switzerland

Biography

Guillaume Philippe of the Master of Science in Medical Biology hosted by the University of Lausanne.Faculty of Biology and Medicine. Ludwig Lausanne Branch Function (s): Research Manager.

Research Interest

 Enhanced cytotoxicity and decreased CD8 dependence of human cancer-specific T cells after vaccination with low peptide dose. Co-expression of the T-cell receptor constant alpha domain triggers tumor reactivity of single-chain TCR-transduced human T cells.

Publications

  • PD-1 and Tim-3 antigen-specific CD8⁺ T cells induced by melanoma vaccines. Fourcade J. , Sun Z. , Pagliano O. , Chauvin JM , Sander C. , et al., (2014). 1045-1055 .

  • In vivo T-cell epitopes and T-cell-based tumor antigen. Schmidt J. , Guillaume P. , Dojcinovic D. , Karbach J. , Coukos G. , et al., (2017).

  • Deciphering HLA-I motifs across HLA peptidomes improves neo-antigen predictions and identifies allostery regulating HLA specificity. Bassani-Sternberg M. , Chong C. , Guillaume P. , Solleder M. , Pak H. , et al., (2017).

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