Stasiak Andrzej
Associate Professor
Faculty of Biology and Medicine
Universite de Lausanne
Switzerland
Biography
Andrzej Stasiak received his PhD in 1981 from the Institute of Biochemistry and Biophysics of Polish Academy of Sciences in Warsaw. From 1981 to 1989 he was a postdoctoral fellow and research associate in the laboratory of Theodor Koller at Institute for Cell Biology, ETHZ, Zurich, Switzerland. In 1989 he joined the Laboratory of Ultra-structural Analysis directed by Jacques Dubochet at the UNIL. In 2007 he joined the Center for Integrative Genomics as Maître d’Enseignement et de Recherche (MER).
Research Interest
The main interest of our group is directed towards understanding the topological aspects of overall organization of genomes starting with the arrangement of DNA in phage heads and ending with chromosome territories in higher eukaryotes.
Publications
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In Search of Functional Advantages of Knots in Proteins Pawel Dabrowski-Tumanski, Andrzej Stasiak, Joanna I. Sulkowska PLoS One. 2016; 11(11):
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How topoisomerase IV can efficiently unknot and decatenate negatively supercoiled DNA molecules without causing their torsional relaxation Eric J. Rawdon, Julien Dorier, Dusan Racko, Kenneth C. Millett, Andrzej Stasiak Nucleic Acids Res. 2016 Jun 2; 44(10):
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Studies of global and local entanglements of individual protein chains using the concept of knotoids Dimos Goundaroulis, Julien Dorier, Fabrizio Benedetti, Andrzej Stasiak Sci Rep. 2017; 7: 6309.