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Dr. Julien Furrer

Lecturer
Department of Chemistry and Biochemistry
Universität Bern
Switzerland

Biography

PD Dr. Julien Furrer in 1975 Born in Strasbourg, France. 1993-1998: Diploma studies in Chemistry and Physical Chemistry, Louis Pasteur University of Strasbourg. Diploma thesis on the development of the High Resolution Magic Angle Spinning (HR-MAS) applied to resin bound molecules, under the guidance of Prof. Dr. Pierre Granger. 1998-2001: PhD thesis in physical chemistry at the University of Louis Pasteur, Strasbourg, under the supervision of Dr. Karim Elbayed and Dr. Martial Piotto. Methodological and Experimental Aspects of the High Resolution Magic Angle Spinning (HR-MAS) NMR Technique. 2001-2004: Alexander von Humboldt Postdoctoral Research Fellow with Prof. Dr. Horst Kessler and Dr. Burkhard Luy, Institute of Organic Chemistry and Biochemistry, TU Munich, Germany. Working on the NMR structural elucidation of peptides and proteins and development of new NMR methods. 2004-2007: Assistant "Academic Council", Head of the NMR Facilities, Organic Chemistry Institute, University of Heidelberg (Germany). 2007-2010: Engineer, Head of the NMR Facilities, Analytical Department, University of Neuchâtel (Switzerland). 2011: Lecturer (Lecturer) at the University of Berne. Head of the NMR spectroscopy group

Research Interest

General principles of our research are the development of novel experimental methods in nuclear magnetic resonance (NMR) spectroscopy, with applications for structural studies of biopolymers and organic compounds. Recently we have started investigating the cytotoxic effect of various ruthenium complexes in cancer cells. The mechanisms involved here are not yet fully understood and we are trying to elucidate them using various NMR measurements.

Publications

  • Gjuroski, Ilche ; Pfister, Sara Bettina ; Furrer, Julien ; Vermathen, Martina (2016). Polymer Delivery Systems of Porphyrin Photosensitizers Monitored by NMR Spectroscopy. CHIMIA, 70 (7/8), MC148. Swiss Chemical Society

  • Geiser, Lennart ; Stibal, David ; Süss-Fink, Georg ; Furrer, Julien (2016). Hydrolytic behavior of mono- and dithiolatho-bridged dinuclear arene ruthenium complexes and their interactions with biological ligands. CHIMIA, 70 (7/8), p. 538. Swiss Chemical Society

  • Brugger, Silvio ; Troxler, Luke ; Rüfenacht, Susanne ; Frey, Pascal Marcel ; Morand, Brigitte ; et al (2016). Polysaccharide capsule composition of pneumococcal serotype 19A subtypes: Unaltered among subtypes and independent of the nutritional environment. Infection and immunity, 84 (11), pp. 3152-3160. American Society for Microbiology 10.1128 / IAI.00474-16

  • Vermathen, Martina ; Diserens, Gaëlle ; Vermathen, Peter ; Furrer, Julien (2017). Metabolic Profiling of Cells in Response to Drug Treatment using 1H High-Resolution Magic Angle Spinning (HR-MAS) NMR Spectroscopy. CHIMIA, 71 (3), pp. 124-129. Swiss Chemical Society

  • Silva Pinto Basto, Afonso ; Mueller, Joachim ; Rubbiani, Riccardo ; Stibal, David ; Giannini, Federico ; et al (2017). Characterization of the Activities of Dinuclear Thiolato-Bridged Arene Ruthenium Complexes against Toxoplasma gondii. Antimicrobial agents and chemotherapy, 61 (9), e01031-17. American Society for Microbiology 10.1128 / AAC.01031-17

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