Dr. Stefan Schurch
Associate Professor
Department of Chemistry and Biochemistry
Universität Bern
Switzerland
Biography
Dr. Stefan Schurch from 1985-1990 Graduate studies in chemistry, University of Berne. 1990-1995 Ph.D. thesis at the Institute of Organic Chemistry, University of Bern (Prof. Urs P. Schlunegger). 1995-1997 Post-doc at the Department of Chemistry, University of California at Riverside (Prof. Charles L. Wilkins). 1997-2003 Assistant to the Department of Chemistry and Biochemistry, University of Bern. Since 1997 Head of the mass spectrometry group. 2003-2016 Lecturer at the Department of Chemistry and Biochemistry. 2007 Venia Docendi in analytical chemistry (Habilitation), Faculty of Science, University of Bern. Since 2017 Associate Professor of Analytical Chemistry, University of Bern
Research Interest
The general focus of research is on the mass spectrometric characterization of nucleic acids and their therapeutically relevant analogues. Besides elucidation of the gas-phase behavior of oligonucleotides, we use mass spectrometry as a tool to gain insight into nucleic acids. Further research activities are performed on a comprehensive characterization of spider hemolymph and venom components.
Publications
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Ambach, Lars ; Hernández Redondo, Ana ; King, Stefan ; Angerer, Verena ; Schuerch, Stefan ; Weinmann, Wolfgang (2015). Detection and quantification of 56 new psychoactive substances in whole blood and urine by LC-MS / MS. Bioanalysis, 7 (9), pp. 1119-1136. Future Science 10.4155 / bio.15.48
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Hari, Yvonne ; Dugovic, Branislav ; Istrate, Alena ; Fignolé, Klavdja Annabel ; Schürch, Stefan (2016). The Contribution of the Activation Entropy to the Gas Phase Stability of Modified Nucleic Acid Duplexes. Journal of the American Society for Mass Spectrometry, 27 (7), pp. 1186-1196. Springer 10.1007 / s13361-016-1391-3
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Hädener, Marianne ; Weinmann, Wolfgang ; Schuerch, Stefan ; King, Stefan (2016). Development of a rapid column-switching LC-MS / MS method for the quantification of THCCOOH and THCCOOH-glucuronide in whole blood for assessing cannabis consumption frequency. Analytical and bioanalytical chemistry, 408 (7), pp. 1953-1962. Springer 10.1007 / s00216-016-9311-8
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Luginbühl, Marc Joel ; Schröck, Alexandra ; King, Stefan ; Schuerch, Stefan ; Weinmann, Wolfgang (2016). Determination of fatty acid ethyl ester in dried blood spots by LC-MS / MS as Analytical and bioanalytical chemistry, 408 (13), pp. 3503-3509. Springer 10.1007 / s00216-016-9426-y
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Schürch, Stefan (2016). The second decade (2004-2013): From DNA to RNA and modified sequences. Mass Spectrometry Reviews, 35 (4), pp. 483-523. Wiley 10.1002 / mas.21442
