Dr. Thomas Kaufmann
Professor
Institute of Pharmacology
Universität Bern
Switzerland
Biography
Dr. THOMAS KAUFMANN Since 2014 Associate Professor, Medical Faculty, University of Bern (CH); 2011 'Venia Docendi' (Habilitation) in Experimental Pharmacology, University of Bern (CH); 2003 PhD in Biochemistry, Institute of Biochemistry, University of Fribourg (CH); 2000 Diploma in Biochemistry, Institute of Biochemistry, University of Fribourg (CH)
Research Interest
Pro-apoptotic family member BOK, Molecular mechanisms of programmed cell death
Publications
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Tuzlak, Selma; Kaufmann, Thomas; Villunger, Andreas (2016). Interrogating the relevance of mitochondrial apoptosis for vertebrate development and postnatal tissue homeostasis. Genes & development, 30(19), pp. 2133-2151. Cold Spring Harbor Laboratory Press 10.1101/gad.289298.116
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Wicki, Simone; Gurzeler, Ursina; Wei-Lynn Wong, W; Bachmann, Daniel; Kaufmann, Thomas; Jost, Philipp (2016). Loss of XIAP facilitates switch to TNFα-induced necroptosis in mouse neutrophils. Cell death & disease, 7(10), e2422. Nature Publishing Group 10.1038/cddis.2016.311
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Hagmann, B R; Odermatt, A; Kaufmann, Thomas; Dahinden, C A; Fux, M (2017). Balance between IL-3 and type Iinterferons and their interrelationship with FasL dictates lifespan and effector functions of human basophils. Clinical and experimental allergy, 47(1), pp. 71-84. Wiley 10.1111/cea.12850
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Fernandez-Marrero, Yuniel; Bleicken, Stephanie; Das, Kushal Kumar; Bachmann, Daniel; Kaufmann, Thomas; Garcia-Saez, Ana J (2017). The membrane activity of BOK involves formation of large, stable toroidal pores and is promoted by cBID. FEBS journal, 284(5), pp. 711-724. Wiley-Blackwell 10.1111/febs.14008
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Haimovici, Aladin; Humbert, Magali; Federzoni, Elena A; Shan-Krauer, Deborah; Brunner, Thomas; Frese, Steffen; Kaufmann, Thomas; Torbett, Bruce E; Tschan, Mario P (2017). PU.1 supports TRAIL-induced cell death by inhibiting NF-κB-mediated cell survival and inducing DR5 expression. Cell death and differentiation, 24(5), pp. 866-877. Nature Publishing Group 10.1038/cdd.2017.40
