Fujita Satoshi
First assistant
Faculty of Biology and Medicine
University of Lausanne
Switzerland
Biography
Fujita Satoshi of the Master of Science in Medical Biology hosted by the University of Lausanne.Faculty of Biology and Medicine. Ludwig Lausanne Branch Function (s): First assistant.
Research Interest
My principal research interests lie in the development of cellular nano-device technology combined with nanotechnology, molecular biology and cell biology. The technologies will become one of the powerful tools for medical application such as drug discovery, theranostic and regenerative therapy. Especially, I have been interested in one of the cell microarrays, transfected cell microarray (TCM), where plasmid DNA and/or siRNA are spotted on the surface of a substrate and are reverse-transfected locally into adherent cells. I believe that TCM will become standard tool for parallel cell-based omics analysis (cellomics). I applied the TCM technology to medical tools and devices as well. My background before getting PhD is molecular biology, cell biology, nucleic chemistry and protein engineering. Therefore, I would like to learn in the field of soft lithography, micro-fabrication and soft interface regulation to fuse each field technologies and make innovative miniaturized device for cell validation. Now, I am progressing project to make the surface where we can easily control the release timing of transfection of plasmid DNA.
Publications
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Alassimone J, Fujita S, Doblas VG, van Dop M, Barberon M, et al., (2016). Polarly localized kinase SGN1 is required for Casparian strip integrity and positioning. Nature plants. 2016 Jul 25;2:16113.
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Kalmbach L, Hématy K, De Bellis D, Barberon M, Fujita S, et al., (2017). Transient cell-specific EXO70A1 activity in the CASP domain and Casparian strip localization. Nature plants. 2017 Apr 24;3:17058.
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Doblas VG, Smakowska-Luzan E, Fujita S, Alassimone J, Barberon M, et al., (2017). Root diffusion barrier control by a vasculature-derived peptide binding to the SGN3 receptor. Science. 2017 Jan 20;355(6322):280-4.