Goloubinoff Pierre
Associate Professor
Faculty of Biology and Medicine
University of Lausanne
Switzerland
Biography
Goloubinoff Pierre of the Master of Science in Medical Biology hosted by the University of Lausanne.Faculty of Biology and Medicine. Ludwig Lausanne Branch Function (s): Associate Professor.
Research Interest
Our long-term goal is to understand the chaperone network in bacteria, plant and human, in order to better prevent protein misfolding and promote the active curing of toxic protein aggregates in bacteria, plants, and especially in the case of protein misfolding diseases in mammals. As model organisms we use enterobacteria, cyanobacteria, the moss Physcomitrella patens and the higher plant Arabidopsis thaliana. Our experimental approaches combine genetics, biochemistry and biophysics.
Publications
-
De Los Rios P, Goloubinoff P. (2016). Hsp70 chaperones use ATP to remodel native protein oligomers and stable aggregates by entropic pulling. Nature structural & molecular biology. 2016 Sep 1;23(9):766-9.
-
Finka A, Mattoo RU, Goloubinoff P. (2016). Experimental milestones in the discovery of molecular chaperones as polypeptide unfolding enzymes. Annual review of biochemistry. 2016 Jun 2;85:715-42.
-
Carra S, Alberti S, Arrigo PA, Benesch JL, Benjamin IJ, et al., (2017). The growing world of small heat shock proteins: from structure to functions. Cell Stress and Chaperones. 2017 Mar 31:1-1.
