Honegger Paul
Faculty of Biology and Medicine
Department of Physiology
University of Lausanne
Switzerland
Biography
Paul Franken received his PhD from the University of Groningen,The Netherlands, in 1993 for his work on sleep homeostasis and thermoregulation at the University of Zurich under the direction of Alexander A. Borbély. He was a postdoctoral fellow with H. Craig Heller at Stanford University, USA, where he studied the cellular mechanisms underlying circadian clock resetting. In 1996 he joined Mehdi Tafti at the University of Geneva where he used QTL analysis to map sleep and EEG traits in mice. He then moved back to Stanford in 2000 as a senior research scientist to establish an independent lab.
Research Interest
At Stanford continued to work on the genetics of sleep homeostasis and further focused on the molecular interactions between circadian rhythms, sleep homeostasis, and brain metabolism. Then joined the CIG in 2005. Sleep and energy homeostasis, circadian clock genes, QTL analysis, genetics of EEG activity.
Publications
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Honegger P, Zurich MG. (2011). Preparation and use of serum-free aggregating brain cell cultures for routine neurotoxicity screening. Cell Culture Techniques. 2011: 105-128.
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Zurich MG, Honegger P. (2011). Ochratoxin A at nanomolar concentration perturbs the homeostasis of neural stem cells in highly differentiated but not in immature three-dimensional brain cell cultures. Toxicology letters. 205: 203-208.
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Zurich MG, Stanzel S, Kopp-Schneider A, Prieto P, Honegger P. (2013). Evaluation of aggregating brain cell cultures for the detection of acute organ-specific toxicity. Toxicology in Vitro. 27: 1416-1424.
