Humbel Bruno
research teacher
Faculty of Biology and Medicine
University of Lausanne
Switzerland
Biography
Dr. Bruno M. Humbel did education in Dipl. natw. ETH in Biochemistry and Dr. sc. nat. ETH in Cell Biology at Federal Institute of Technology, Zürich, Switzerland, Post-doc in Cell Biology at the Max-Planck- Institute for Biochemistry, Martinsried, Germany worked as assistant Professor in Molecular Cell Biology and as associate Professor in Molecular Cell Biology at Utrecht University, Utrecht, The Netherlands Currently he is Head of the Facility of Electron Microscopy at University of Lausanne, Lausanne, Switzerland. and honoured with JSPS Fellowship at Japan Women's University, Tokyo, Japan also visiting Professor at National Institute for Physiological Sciences, Okazaki, Japan
Research Interest
Dr Humbel's research focuses on sample preparation for optimal, life-like imaging of biological objects in the electron microscope. His main interests are preparation methods based on cryo-fixation. From here hybrid follow-up methods like freeze-substitution or freeze-fracture are used. Since a couple of years he is shifting to imaging modes and was lucky enough to be close to the cradle of the integrated light-electron microscope developed by his colleagues in Utrecht. In Lausanne, the main development lines are correlative microscopy and FIB-SEM tomography.
Publications
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Garroum I, Bidzinski P, Daraspe J, Mucciolo A, Humbel BM, et al., (2016) Cuticular defects in Oryza sativa ATP-binding cassette transporter G31 mutant plants cause dwarfism, elevated defense responses and pathogen resistance. Plant and Cell Physiology. 57: 1179-88.
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Mazurek S, Garroum I, Daraspe J, Mucciolo A, Humbel BM et al., (2017) Connecting the molecular structure of cutin to ultrastructure and physical properties of the cuticle in petals of Arabidopsis. Plant Physiology. 173: 1146-1163.
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Meier AF, Suter M, Schraner EM, Humbel BM, Tobler K, et al., (2017). Transfer of Anti-Rotavirus Antibodies during Pregnancy and in Milk Following Maternal Vaccination with a Herpes Simplex Virus Type-1 Amplicon Vector. International journal of molecular sciences. 18: 431.