Mach Jean-pierre
Faculty of Biology and Medicine
Department of Biochemistry
University of Lausanne
Switzerland
Biography
Jean-Pierre Mach received his medical degree at the University of Geneva and trained from 1963 to 1967 as a postdoctoral fellow at the Massachussetts General Hospital in Boston. He specialized in the field of tumor markers at the Department of Biochemistry of our University where he became professor in 1976. From 1978 to 1986, he was associate director of the Lausanne branch from the Ludwig Institute. At his retirement from a double appointment at ISREC and our University, he joined Prof. G. Corradin's group to pursue his research with Dr Alena Donda, project leader, on antibody-mediated targeting of antigenic MHC class I complexes and MHC related molecules on tumor cells.
Research Interest
CANCER: ANTIBODY-MEDIATED TUMOR TARGETING OF MHC-RELATED MOLECULE CD1d
Publications
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Ulmer AJ, Kaconis Y, Heinbockel L, Correa W, Alexander C, et al., (2016). Enhancing actions of peptides derived from the γ-chain of fetal human hemoglobin on the immunostimulant activities of monophosphoryl lipid A. Innate immunity. 2016 Apr;22(3):168-80.
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Golay J, Choblet S, Iwaszkiewicz J, Cérutti P, Ozil A, et al., (2016). Design and Validation of a Novel Generic Platform for the Production of Tetravalent IgG1-like Bispecific Antibodies. The Journal of Immunology. 2016 Apr 1;196(7):3199-211.
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Gorczynski RM, Alexander C, Brandenburg K, Chen Z, Heini A, et al., (2017). An altered REDOX environment, assisted by over-expression of fetal hemoglobins, protects from inflammatory colitis and reduces inflammatory cytokine expression. International Immunopharmacology. 2017 Sep 1;50:69-76.
