Martinon Fabio
Faculty of Biology and Medicine
Department of Biochemistry
University of Lausanne
Switzerland
Biography
Fabio Martinon received his PhD in 2003 from the University of Lausanne for his work on the characterization of the Inflammasome in the laboratory of Jürg Tschopp. After a short post-doctoral fellowship in Jürg Tschopp’s laboratory, he moved in 2006 to the laboratory of Laurie Glimcher at the Harvard School of Public Health, where he investigated the link between inflammatory programs and the endoplasmic reticulum stress response. In August 2010 he joined the Department of Biochemistry as Assistant Professor. His current research focuses on the characterization of signaling pathways emerging from the endoplasmic reticulum.
Research Interest
Cellular stress is a hallmark of severe pathogenic insults that leads to the activation of adaptation programs aimed at restoring tissue homeostasis. This state of reversible malfunction is defined by the notion of stress. Tissue stress and malfunction promotes low-grade inflammation that helps the tissue to cope with damage and restore tissue function.
Publications
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De Gassart A, Martinon F. (2017). Translating the anticancer properties of eEF2K. Cell Cycle. 2017 Feb 16;16(4):299-300.
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Bujisic B, Martinon F. (2017). IRE1 gives weight to obesity-associated inflammation. Nature Immunology. 2017 May 1;18(5):479-80.
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Bujisic B, De Gassart A, Tallant R, Demaria O, Zaffalon L, et al., (2017). Impairment of both IRE1 expression and XBP1 activation is a hallmark of GCB DLBCL and contributes to tumor growth. Blood. 2017 Apr 27;129(17):2420-8.
