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Toxicology Experts

Tappy Luc

Faculty of Biology and Medicine
Department of Physiology
University of Lausanne
Switzerland

Biography

Luc Tappy obtained his MD degree at the University of Lausanne in 1981, and was trained in the Department of Internal Medicine and the Service of Endocrinology, Centre Hospitalier Universitaire Vaudois (CHUV) and in the Diabetes section, Temple University Hospital, Philadelphia, PA, USA. 

Research Interest

Identifying environmental (diet, physical activity, toxins…) factors involved in the development of metabolic diseases.Making the bridge between basic cellular and animal research and human pathologies.Assessing the effects and efficiency of novel treatment for metabolic diseases (drugs, functional nutrients).Implementing novel approaches for the prevention of chronic diseases through physical activity  For our studies we rely on standard functional metabolic tests (oral glucose tolerance tests, hyperinsulinemic/hyperglycemic clamps, etc) together with indirect calorimetry, kinetic evaluation of substrate metabolism with the use of stable-labeled isotopes, in-vivo magnetic resonance spectroscopy, functional evaluation of brain function using tridimensional EEG recordings, and genomic /proteomic approaches on tissue biopsies.     

Publications

  • Tappy L, Rosset R. (2017). Fructose metabolism from a functional perspective: Implications for athletes. Sports Medicine. 22: 1-10.

  • Rosset R, Lecoultre V, Egli L, Cros J, Rey V, et al., (2017). Endurance Training with or without Glucose-Fructose Ingestion: Effects on Lactate Metabolism Assessed in a Randomized Clinical Trial on Sedentary Men. Nutrients. 9: 411.

  • Tuzson B, Jagerska J, Looser H, Graf M, Felder F, et al., (2017). Highly Selective Volatile Organic Compounds Breath Analysis Using a Broadly-Tunable Vertical-External-Cavity Surface-Emitting Laser. ANALYTICAL CHEMISTRY. 89: 6377-6383.

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