Xiong Zhao
Professor
Molecular Chemistry and Cell Biology
China Medical University
Taiwan
Biography
Dr. Hsiung's current research interests include statistical genetics/genomics and genetic epidemiology. Her research team have participated in an international genetic study─Stanford Asia Pacific Program in Hypertension and Insulin Resistance (SAPPHIRe). Collaborating with several medical centers in Taiwan, Hawaii and San Francisco Bay Area, they have recruited over one thousand sibpairs. Many clinical and environmental data are collected and analyzed, which resulted in many good publications in international journals. We have also been collaborating with Washington University at St. Louis to study rare variants in hypertension among Chinese. The research team have also established the Genetic Epidemiological Study of Lung Adenocarcinoma (GELAC) by collaborating with six hospitals in Taiwan. Recently they have collaborated with NCI of NIH-US on non-smoking female lung cancer and other topics. The research team have published a series papers on genetic determinants of lung cancer, including the recent paper published in Nature Genetics and PLoS Genetics on GWAS finding and its replicates by international consortium. Her laboratory also puts efforts on statistics in genomic research such as microarray analysis for time course gene expression data and array CGH data. In addition to genetics/genomics research, they also put efforts on modeling and analysis of infectious disease data. Her work is to use statistical approach to help solve biomedical problems and to develop statistical methodologies for problems rising from real biomedical applications.
Research Interest
Biostatistics, Survival Analysis, Statistical Genetics, Genetic Epidemiology, Statistics in Genomic Research
Publications
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Chien LC. †, Wu YJ. †, Hsiung CA., Wang LH. and Chang IS. (2015). Smoothed Lexis diagrams with applications to lung and breast cancer trends in Taiwan. Journal of the American Statistical Association (In press) (†The two authors are the joint first authors).
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Chiu YF, Hsu CC, Chiu TH, Lee CY, Liu TT, Tsao CK, Chuang SC, Hsiung CA. “Cross-sectional and longitudinal comparisons of metabolic profiles between vegetarian and non-vegetarian subjects: a matched cohort study.†British Journal of Nutrition 2015 Sep.
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Chen KY, Hsiao CF, Chang GC, Tsai YH, Su WC, Chen YM, Huang MS, Tsai FY, Jiang SS, Chang IS, Chen CY, Hsiung CA+, Chen CJ, Yang PC,+. “Circulating Interleukin-6 level is a prognostic marker for survival in advanced non-small cell lung cancer patients treated with chemotherapy.†Journal of Thoracic Oncology 2015 Aug.
