Jung-hsia Hsu
Associate Professor
Life Science
National Dong Hwa University
Taiwan
Biography
From year 2004 – present he is working in Department of Life Science and Institute of Biotechnology, National Dong Hwa University as an Associate Professor. He completed his PhD (Department of Biological Sciences, Purdue University Biochemistry Program), Purdue University, 1986.
Research Interest
Downstream effectors of PI3 K/AKT signaling pathway in myeloma cells, Tyrosin kinases and tyrosin phosphatases in IL-6 signaling pathways in myeloma cells, Signaling pathways and virus replication.
Publications
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Gera JF, Mellinghoff IK, Shi Y, Rettig MB, Tran C, Hsu JH, Sawyers CL, and Lichtenstein AK. AKT activity determines sensitivity to mTOR inhibitors by regulating cycline D1 and c-myc expression. J. Biol. Chem. 279(4)(2004)2737-2746.
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Hsu JH, Shi Y, Frost P, Yan H, Hoang B, Sharma S, Gera J, and Lichtenstein A. Interleukin-6 activates phosphoinositol-3’ kinase in multiple myeloma tumor cells by signaling through RAS-dependent and, separately, through p85-dependent pathways. Oncogene 23(2004)3368-3375.
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Ho YP, Kuo CW, Hsu YT, Huang YS, Yew LP, Huang WF, Lin KC, and Hsu JH. b-actin is a downstream effector of the PI3K/AKT signaling pathway in myeloma cells. Mol Cell Biochem 348(2011)129-139.
