Immunology
Global

Immunology Experts

Hsin-wei Chen


Microbiology and Immunology
National Health Research Institutes
Taiwan

Biography

Hsin-Wei Chen has initiated the development of dengue vaccines project in NHRI. His team has developed a novel dengue vaccine candidate that induces cross-neutralizing antibodies and memory immunity. Most important, they developed recombinant lipidated dengue subunit vaccine candidates. These candidates independently stimulate long-lasting neutralizing antibodies and reduce the risk of antibody-dependent enhancement. The immune responses induced by the tetravalent formulation in the absence of the exogenous adjuvant are functional in clearing the 4 serotypes of dengue virus in vivo. Hsin-Wei Chen has initiated the development of dengue vaccines project in NHRI. His team has developed a novel dengue vaccine candidate that induces cross-neutralizing antibodies and memory immunity. Most important, they developed recombinant lipidated dengue subunit vaccine candidates. These candidates independently stimulate long-lasting neutralizing antibodies and reduce the risk of antibody-dependent enhancement. The immune responses induced by the tetravalent formulation in the absence of the exogenous adjuvant are functional in clearing the 4 serotypes of dengue virus in vivo.

Research Interest

Vaccines and Immunology

Global Experts from Taiwan

Global Experts in Subject

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