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James Mickelson


Department of Veterinary and Biomedical Sciences
Vector Control Research Centre
Ukraine

Biography

Dr. James Mickelson is currently working as a Professor in the Department of Department of Veterinary and Biomedical Sciences, Vector Scientific, Inc. , United States of America. His research interests includes Dr. Mickelson is an expert in the molecular and genetic basis of neuromuscular disease in animals. His group has identified genes for inherited neuromuscular diseases in both horses (overo lethal white syndrome, glycogen branching enzyme deficiency, polysaccharide storage myopathy) and dogs (malignant hyperthermia, exercise-induced collapse, polyneuropathies) that serve as comparative animal models for several human conditions. He is currently performing genetic association analyses for exertional rhabdomyolysis in horses, as well as several forms of canine idiopathic epilepsy, exercise collapse, leukoencephalomyelopathy and polyneuropathies.. He /she is serving as an editorial member and reviewer of several international reputed journals. Dr. James Mickelson is the member of many international affiliations. He/ She has successfully completed his Administrative responsibilities. He /she has authored of many research articles/books related to Dr. Mickelson is an expert in the molecular and genetic basis of neuromuscular disease in animals. His group has identified genes for inherited neuromuscular diseases in both horses (overo lethal white syndrome, glycogen branching enzyme deficiency, polysaccharide storage myopathy) and dogs (malignant hyperthermia, exercise-induced collapse, polyneuropathies) that serve as comparative animal models for several human conditions. He is currently performing genetic association analyses for exertional rhabdomyolysis in horses, as well as several forms of canine idiopathic epilepsy, exercise collapse, leukoencephalomyelopathy and polyneuropathies..

Research Interest

Dr. Mickelson is an expert in the molecular and genetic basis of neuromuscular disease in animals. His group has identified genes for inherited neuromuscular diseases in both horses (overo lethal white syndrome, glycogen branching enzyme deficiency, polysaccharide storage myopathy) and dogs (malignant hyperthermia, exercise-induced collapse, polyneuropathies) that serve as comparative animal models for several human conditions. He is currently performing genetic association analyses for exertional rhabdomyolysis in horses, as well as several forms of canine idiopathic epilepsy, exercise collapse, leukoencephalomyelopathy and polyneuropathies.

Publications

  • Fill M, Coronado R, Mickelson JR, Vilven J, Ma JJ, Jacobson BA, Louis CF. Abnormal ryanodine receptor channels in malignant hyperthermia. Biophysical Journal. 1990 Mar 1;57(3):471-5.

  • Mickelson JR, Louis CF. Malignant hyperthermia: excitation-contraction coupling, Ca2+ release channel, and cell Ca2+ regulation defects. Physiological Reviews. 1996 Apr 1;76(2):537-92.

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