J Topping
Assistant Professor
Department of Biosciences
Durham University
United Kingdom
Biography
My first degree was in Molecular Biology at Glasgow University, after which I moved east to Edinburgh to study for a PhD under the supervision of Prof Chris Leaver FRS. During my PhD I applied the (then) new tools of molecular biology to a study of the transcriptional regulation of plant organellar and nuclear genomes during monocot leaf development. After completing my doctorate, I moved to Rothamsted Research to work on the genetic transformation of monocot species. Having gained a strong background in molecular and genetic transformation I then moved to Leicester University where, using Arabidopsis as a model plant species, Keith Lindsey and I established a novel molecular strategy to identify and clone both regulatory elements and genes essential for plant growth and development. This technique, known as Promoter Trapping, became established as a valuable strategy for the isolation and characterization of plant genes.
Research Interest
Research interests are Molecular Plant Sciences.
Publications
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Casson, S.A., Topping, J.F. & Lindsey, K. (2009). MERISTEM-DEFECTIVE, an RS domain protein, is required for the correct meristem patterning and function in Arabidopsis. The Plant Journal 57(5): 857-869.
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Moore, S., Zhang, X., Mudge, A., Rowe, J., Topping, J., Liu, J. & Lindsey, K. (2015). Spatiotemporal modelling of hormonal crosstalk explains the level and patterning of hormones and gene expression in Arabidopsis thaliana wildtype and mutant roots. New Phytologist 207(4): 1110-1122.
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Rowe, J., Topping, J.F., Liu, J. & Lindsey, K. (2016). Abscisic acid regulates root growth under osmotic stress conditions via an interacting hormonal network with cytokinin, ethylene and auxin. New Phytologist 211(1): 225-239.
