Hasan Yardimci
physics
Francis Crick Institute
United Kingdom
Biography
Hasan Yardimci obtained a BSc degree in physics from Bogazici University, Turkey, in 1999. He then joined the graduate program of Johns Hopkins University and received his PhD in soft condensed matter physics in 2006. As a postdoctoral research fellow at University of Illinois at Urbana-Champaign (2006-2008), Hasan studied the molecular mechanism of a mitotic kinesin using single molecule imaging methods. He then moved to Harvard Medical School (2008-2013) as a postdoc, where he focused on single molecule studies of eukaryotic DNA replication. In 2013, Hasan established his own research group at Clare Hall Laboratories, Cancer Research UK London Research Institute (now part of the Francis Crick Institute). His laboratory develops and applies novel single molecule tools to study DNA replication and repair.
Research Interest
His current research interest is to study eukaryotic DNA replication at the single-molecule level that will lend important new insights into the mechanism and dynamics of the complex molecular machines that carry out genome duplication.
Publications
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Yardimci H, Wang X, Loveland AB, Tappin I, Rudner DZ. Hurwitz J, van Oijen AM, Walter JC.. Bypass of a protein barrier by a replicative DNA helicase. Nature, 2012;492:205
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Yardimci H, Loveland AB., van Oijen AM, Walter JC. Single-molecule analysis of DNA replication in Xenopus egg extracts. Methods, 2012;57:179
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Yardimci H, Walter JC. Prereplication-complex formation: a molecular double take? Nat Struct Mol Biol. 2014; 21:20-25
