Tonia vincent
Professor
Biology
Kennedy Institute of Rheumatology Trust (Charing Cross Sunley Research Centre)
United Kingdom
Biography
Education: Tonia Vincent studied medicine at UCL, qualifying in 1993. She trained as a junior doctor in London, later specialising in Rheumatology. In 1998 she took time out to do a PhD at the Kennedy Institute of Rheumatology under Professor Jeremy Saklatvala. She continued at the Kennedy Institute as a Wellcome Trust clinician scientist and is currently an Arthritis Research UK Senior Fellow. In 2012 the Kennedy Institute moved to the University of Oxford and she was appointed Professor of Musculoskeletal Biology. Research Interests: Her research interests include pathways that drive mechanosensitive responses in cartilage, the role of the pericellular matrix in determining these responses and how they modulate osteoarthritis in vivo. She published more than 100 articles.
Research Interest
Biology
Publications
-
1. Vincent T, Malfait AM Time to be positive about negative data? Osteoarthritis Cartilage (2017) 25: 351-353 2. Gorvin CM, Hannan FM, Howles SA, Babinsky VN, Piret SE, Rogers A Vincent TL Gα11 mutation in mice causes hypocalcemia rectifiable by calcilytic therapy JCI Insight (2017) Vol 2 3. Das Neves Borges P, Vincent TL, Marenzana M Automated assessment of bone changes in cross-sectional micro-CT studies of murine experimental osteoarthritis PLoS One (2017) Vol 12 4. Miotla Zarebska J, Chanalaris A, Driscoll C, Burleigh A, Miller RE, Malfait AM, Stott B, Vincent TL. CCL2 and CCR2 regulate pain-related behaviour and early gene expression in post-traumatic murine osteoarthritis but contribute little to chondropathy. Osteoarthritis Cartilage (2017) 25: 406-412. 5. Ismail HM, Didangelos A, Vincent TL, Saklatvala J. Rapid Activation of Transforming Growth Factor β-Activated Kinase 1 in Chondrocytes by Phosphorylation and K(63) -Linked Polyubiquitination Upon Injury to Animal Articular Cartilage. Arthritis Rheumatol (2017) 69: 565-575.
