Dorine Swinkels

Biography

In her research, Professor Swinkels seeks a comprehensive understanding of iron metabolism, in particular by identifying and characterising novel factors that affect dysregulation of iron homeostasis in human disorders among which are some of the world's most prevalent diseases, such as anaemia of chronic kidney disease, hereditary haemochromatosis, inherited (iron loading) anaemias and bacterial and malarial infections. Translating research findings into novel diagnostic assays and therapeutic strategies that can be implemented in the clinic is a key part of Professor Swinkels’ work. The most recent achievements and activities include developing and harmonising assays for the recently discovered iron regulatory hormone peptide hepcidin, which is the subject of several translational studies. In her research, Professor Swinkels seeks a comprehensive understanding of iron metabolism, in particular by identifying and characterising novel factors that affect dysregulation of iron homeostasis in human disorders among which are some of the world's most prevalent diseases, such as anaemia of chronic kidney disease, hereditary haemochromatosis, inherited (iron loading) anaemias and bacterial and malarial infections. Translating research findings into novel diagnostic assays and therapeutic strategies that can be implemented in the clinic is a key part of Professor Swinkels’ work. The most recent achievements and activities include developing and harmonising assays for the recently discovered iron regulatory hormone peptide hepcidin, which is the subject of several translational studies.

Research Interest

Pharmaceutical Sciences