John Schwabe
Molecular and Cell Biology
Leicester Royal Infirmary
United Kingdom
Biography
Dr. John Schwabe is currently working as a Professor in the Department of Molecular and Cell Biology, Leicester Royal Infirmary , United Kingdom. His research interests includes Structural Biology: NMR Spectroscopy & X-ray Crystallography. He is serving as an editorial member and reviewer of several international reputed journals. Dr. John Schwabe is the member of many international affiliations. He has successfully completed his Administrative responsibilities. He has authored of many research articles/books related to Structural Biology: NMR Spectroscopy & X-ray Crystallography.
Research Interest
Structural Biology: NMR Spectroscopy & X-ray Crystallography, Molecular mechanisms of the regulation of gene expression, Nuclear receptors and their role in metabolism, development and disease.
Publications
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Jamaladdin, S., Kelly, R.D.W., O'Regan, L., Dovey, O.M., Hodson, G.E., Millard, C.J., Portolano, N., Fry, A.M., Schwabe, J.W.R., Cowley, S.M. Histone deacetylase (HDAC) 1 and 2 are essential for accurate cell division and the pluripotency of embryonic stem cells. Proc Natl Acad Sci USA (2014) 111, 9840–9845.
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Nettleship, J.E., Watson, P.J., Rahman-Huq, N., Fairall, L., Posner, M.G., Upadhyay, A.,
 Reddivari, Y., Chamberlain, J.M.G., Kolstoe, S.E., Bagby,S., Schwabe,J.W.R., and Owens,R.J. Transient Expression in HEK 293 Cells: An Alternative 
to E. coli for the Production of Secreted and Intracellular Mammalian Proteins. Insoluble Proteins: Methods and Protocols, Methods in Molecular Biology, vol. 1258, Chapter 11, 209-222. DOI 10.1007/978-1-4939-2205-5_11, © Springer Science+Business Media New York 2015.
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Itoh, T., Fairall, L., Muskett, F. W., Milano, C. P., Watson, P. J., Arnaudo, N., Saleh, A., Millard, C.J., El-Mezgueldi, M., Martino, F., Schwabe, J.W.R. Structural and functional characterization of a cell cycle associated HDAC1/2 complex reveals the structural basis for complex assembly and nucleosome targeting. Nucleic Acids Res. (2015). doi:10.1093/nar/gkv068
