Raman Das
MRC Career Development Fellow
Developmental Biology & Medicine
University of Manchester
United Kingdom
Biography
Work in our lab focuses on understanding the cell biology of neuronal differentiation during development. We use the embryonic spinal cord as our model system and utilise cutting-edge live tissue imaging techniques to image cell behaviour leading to neuronal differentiation in this tissue. The overall aim of our work is to understand how the complicated molecular changes taking place during neurogenesis are translated into the striking cell behaviour that physically drives this process, with the longer term goal of devising strategies to prevent or relieve the symptoms of neurodevelopmental diseases and dementia.
Research Interest
Developmental Biology & Medicine
Publications
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Mitotic spindle orientation can direct cell fate and bias Notch activity in chick neural tube.
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Apical abscission alters cell polarity and dismantles the primary cilium during neurogenesis.
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Major transcriptome re-organisation and abrupt changes in signalling, cell cycle and chromatin regulation at neural differentiation in vivo.
