Silvia Bulfone-paus
Professor
Immunobiology
University of Manchester
United Kingdom
Biography
Silvia Bulfone-Paus is an Italian immunologist who studied Medicine at Turin University where she graduated in 1989. She went on to study Genetics at Yale University (PhD: 1994). Silvia’s first academic appointment was at the Freie Universität Berlin, Institute of Immunology, in 1994 as a senior scientist. Here, she became Deputy Director in 1996 and Assistant Professor in 1999. In 2000 she was appointed Full Professor at the University of Lübeck and Director of the Department of Immunology and Cell Biology at the Research Centre Borstel. From 2006-2008, she served as Managing Director of the Centre. Professor Bulfone-Paus is a member of the Division of Musculoskeletal and Dermatological Sciences and has joined in 2013 the Manchester Collaborative Centre for Inflammation Research (MCCIR).
Research Interest
Silvia’s research focuses on the role of mast cells in tissue homeostasis and pathogenesis. Currently, she is most interested in dissecting the role of mast cells in regulating interactions between innate and acquired immunity.
Publications
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IL-15 suppresses colitis-associated colon carcinogenesis by inducing anti-tumor immunity
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High dose CD11c-driven IL15 is sufficient to drive NK cell maturation and anti-tumor activity in a trans-presentation independent manner
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CD252 regulates mast cell mediated, CD1d-restricted NKT-cell activation in mice
