Jacques Behmoaras
Senior Lecturer
Faculty of Medicine
National Heart Lung Institute
United Kingdom
Biography
I established my research group at Imperial College London in 2010 within the Centre of Complement and Inflammation Research, Division of Immunology and inflammation. The group received funding from the Medical Research Council, Wellcome Trust and Kidney Research UK. Our main interest in to understand genetic variation that controls macrophage function and to establish the link between genome-macrophage function-complex disorders. We use animal models (rats and mice) of inflammatory kidney disease, wound healing and fibrosis and apply systems-genetics approaches to investigate the effect of germline sequence variation on macrophage plasticity. In addition, our recent approaches pointed towards the importance of macrophage metabolism in inflammatory disease.
Research Interest
Inflammation Research
Publications
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2017 Chen TD, Rotival M, Chiu LY, Bagnati M, Ko JH, Srivastava PK, Petretto E, Pusey CD, Lai PC, Aitman TJ, Cook HT and Behmoaras J. Identification of Ceruloplasmin as a Gene that Affects Susceptibility to Glomerulonephritis Through Macrophage Function. Genetics. 2017 Jun;206(2):1139-1151.
