Michael Johnson
Professor
Faculty of Medicine
National Heart Lung Institute
United Kingdom
Biography
I am Professor of Neurology and Genomic Medicine at Imperial College London, and Honorary Consultant Neurologist at Imperial College Healthcare NHS Trust. My research focuses on the systems-level integration of genetic, genomic and phenotypic data to identify causal functional networks and pathways underlying neurological disease. Using systems-level approaches, disease-associated functional networks are then used to identify novel therapeutic targets and drugs which cannot otherwise be captured using traditional genetic strategies based on single-gene analysis. My research is funded by the MRC, UCB Pharma, the NIHR Biomedical Research Centres Scheme, the EU FP7 Framework and the Brain Tumour Research Campaign (www.wayahead-btrc.org). My clinical activity is in general neurology and epilepsy with a particular focus on the autoimmune and tumour associated epilepsies. I am a core member of the Imperial College Healthcare neuro-oncology multidisciplinary team. I am member of the International League Against Epilepsy (ILAE) Task Force on Pharmacogenetics, the Epi4K, EpiPGx and EPITARGET international consortia in epilepsy, Epilepsy Action's Scientific Awards Panel, and advisor to the Commonwealth Scholarship Commission, the UK Parliamentary Health Ombudsman and the British Motor Sports Association.
Research Interest
Neurology
Publications
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Delahaye-Duriez A, Srivastava P, Shkura K, et al., 2016, Rare and common epilepsies converge on a shared gene regulatory network providing opportunities for novel antiepileptic drug discovery, Genome Biology, Vol:17, ISSN:1474-760X