Tobias Buchborn
Researcher
Faculty of Medicine
National Heart Lung Institute
United Kingdom
Biography
Tobias Buchborn studied Psychology at the Otto-von-Guericke University in Magdeburg, Germany. In his Diploma thesis, he investigated the behavioural and pharmacodynamic effects of the 5-HT1A/2A agonist LSD on bulbectomised rats, an animal model of depression. Tobias ran his PhD project in Neuroscience at the Institute of Pharmacology and Toxicology in Magdeburg. Here, his research addressed the behavioural and molecular biological correlates of tolerance to serotonergic hallucinogens, with focus on processes of 5-HT2A regulation. Currently, Tobias works as a MSCA Individual Research Fellow at the Department of Medicine, Laboratory for Neuronal Circuit Dynamics, where he applies voltage imaging techniques to investigate the 5-HT2A-glutamatergic corticodynamics of serotonergic hallucinogens
Research Interest
Psychology
Publications
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Buchborn T, Grecksch G, Dieterich DC, Höllt V (2016). Tolerance to lysergic acid diethylamide (LSD): Overview, correlates, and clinical implications. In: Preedy VR (ed.), Neuropathology of Drug Addictions and Substance Misuse, Volume 2: Stimulants, Club and Dissociative Drugs, Hallucinogens, Steroids, Inhalants and International Aspects, 846-858. Academic Press. doi:10.1016/B978-0-12-800212-4.00079-0.
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Buchborn T, Schröder H, Dieterich DC, Grecksch G, Höllt V (2015). Tolerance to LSD and DOB induced Shaking behaviour: Differential adaptations of frontocortical 5-HT2A and glutamate receptor binding sites. Behav. Brain Res., 281, 62–68. doi:10.1016/j.bbr.2014.12.014.
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Buchborn T, Schröder H, Höllt V, Grecksch G (2014). Repeated lysergic acid diethylamide in an animal model of depression: Normalisation of learning behaviour and hippocampal serotonin 5-HT2 signalling. J. Psychopharmacol., 28, 6, 545-552. doi: 10.1177/0269881114531666.
