Prof Bruijn De Joost

Biography

Joost D. de Bruijn, BSc, PhD, received his PhD Cum Laude from Leiden University (The Netherlands) in 1993 for his doctoral thesis ??Bone Bonding and Biodegradation of Calcium Phosphates?. During his PhD, he spend one year at the Centre for Biomaterials of the University of Toronto (Canada) under the guidance of Prof. JE Davies. After his post-doc period at the Biomaterials Research Group, Leiden University, Joost joined IsoTis BV in 1996 where he was responsible for the bone tissue engineering programme.  As Research Director Bone at IsoTis SA, Joost headed a research group of about 20 post-docs, PhD students, technicians and MSc students. Strong research efforts were directed towards the use of autologous osteoprogenitor cells in combination with biomaterial scaffolds. With this proprietary technique, for which he has received and submitted several patents and received the 6.5 MEuro Brite-EuRam grant ??IsoBone: A Tissue Engineered Living Bone Equivalent??, de Bruijn?s group aimed to culture hybrid implant materials that mimic autologous bone graft. This research has led to the initiation of feasibility clinical trials in which 21 patients were implanted with their own cultured bone.  

Research Interest

Hard tissue replacement, bone tissue engineering, regenerative medicine, synthetic osteoinductive materials, bioreactor systems for adult stem cell expansion