John Gupton
Chemistry
Richmond American International University in London
United Kingdom
Biography
Dr. Gupton's primary research interests involve developing new organic reactions that can be applied to the synthesis of bioactive compounds in agriculture and medicine. More specifically, he has studied for some time the preparation and reactions of novel vinylogous iminium salts as building blocks for the construction of highly functionalized heterocycles. In recent years this work has focused on the preparation of pyrroles by this methodolgy and the subsequent application to the synthesis of bioactive marine natural products which contain the pyrrole ring system.
Research Interest
Organic Chemistry
Publications
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Kase K, Katayama M, Konno T, Ishihara T, Yamanaka H, Gupton JT. Reaction of β-trifluoroethoxy vinamidinium salts with carbon nucleophiles. Journal of fluorine chemistry. 2003 Mar 1;120(1):33-9.
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Gupton JT, Krumpe KE, Burnham BS, Webb TM, Shuford JS, Sikorski JA. The application of vinylogous iminium salt derivatives to a regiocontrolled and efficient relay synthesis of lukianol A and related marine natural products. Tetrahedron. 1999 Dec 17;55(51):14515-22.
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Gupton JT, Clough SC, Miller RB, Norwood BK, Hickenboth CR, Chertudi IB, Cutro SR, Petrich SA, Hicks FA, Wilkinson DR, Sikorski JA. The application of vinylogous iminium salt derivatives to the regiocontrolled preparation of heterocyclic appended pyrazoles. Tetrahedron. 2002 Jul 1;58(27):5467-74.
