Sean Chapman
Electron Microscopist
Cell and Molecular Sciences
Scottish Crop Research Institute
United Kingdom
Biography
2006-Present: Grade E, Molecular Plant Pathologist and Electron Microscopist 2002-2006: Band 5SPD, Plant Cell Biologist, SCRI 1999-2002: Band 5SPD, Molecular Virologist, Mylnefield Research Services 1997-1999: Senior Scientist, Axis Genetics plc, Cambridge 1994-1997: Band 6PD, Virologist, SCRI 1992-1994: Post- Doctoral Research Assistant, Citrus Research and Education Centre, Florida 1991-1992: Post- Doctoral Research Assistant, TSL, John Innes Centre
Research Interest
The major focus of my research is on developing durable resistance against the potato pathogen Phytophthora infestans that causes late blight, the most important disease of potatoes. Work at the James Hutton Institute has identified proteins secreted by the pathogen to overcome innate host resistance and some of these effector proteins have been shown to be essential for pathogenicity. In response plants have evolved resistance proteins that recognise effector proteins and trigger resistance responses to prevent infection. In turn pathogens have evolved effector alleles that evade R gene recognition.
Publications
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Wright, K., Chapman, S., McGeachy, K., Humphris, S., Campbell, E., Toth, I. and Holden, N. 2013. The endophytic lifestyle of Escherichia coli 0157:H7: quantification and internal localisation in roots. Phytopathology 103, 333-340
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Tilsner, J., Linnik, O., Louveaux, M., Roberts, I.M., Chapman, S.N., Oparka, K.J. 2013. Replication and trafficking of a plant virus are coupled at the entrances of plasmodesmata. Journal of Cell Biology 201, 981-995.
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Pasare, S., Wright, K., Campbell, R., Morris, W., Ducreux, L., Chapman, S., Bramley, P., Fraser, P., Roberts, A. and Taylor, M. 2013. The sub-cellular localisation of the potato (Solanum tuberosum L.) carotenoid biosynthetic enzymes, CrtRb2 and PSY2. Protoplasma. (doi: 10.1007/s00709-013-0521-z)
