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Molecular Biology Experts

Xinwei Chen

Molecular Geneticist
Cell and Molecular Sciences
Scottish Crop Research Institute
United Kingdom

Biography

BSc (Agricultural Botany), Huazhong Agricultural University, Wuhan, China, 1985 PhD (Genetics), University of Cologne, Koeln, Germany, 2000

Research Interest

Leaf rust caused by Puccinia hordei is an important fungal disease on barley. Resistance of barley to leaf rust (Poccinia hordei) is genetically controlled by both single genes (R-genes) and multiple quantitative loci (QTL). Due to the short-term effectiveness of R-gene-mediated resistance, exploration and use of the durable partial resistance have become a more favorable strategy to control the disease. However, identification of the underlying genes through map-based approach is a process both cumbersome and time consuming.

Publications

  • Chen, X., Hackett, C.A., Niks, R.E., Hedley, P.E., Booth, C., Druka, A., Marcel, T.C., Vels, A., Bayer, M., Milne, I., Morris, J., Ramsay, L., Marshall, D., Cardle, L., Waugh, R. 2010. An eQTL Analysis of Partial Resistance to Puccinia hordei in Barley. PLoS ONE 5(1), e8598.

  • Chen, X., Niks, R.E., Hedley, P.E., Morris, J., Druka, A., Marcel, T.C., Vels, A., Waugh, R. 2010. Differential gene expression in nearly isogenic lines with QTL for partial resistance to Puccinia hordei in barley. BMC Genomics 11, 629.

  • Chen. X., Hedley, P.E., Morris, J., Liu, H., Niks, R.E., Waugh, R. 2011. Combining genetical genomics and bulked segregant analysis-based differential expression: an approach to gene localization. Theoretical and Applied Genetics 122(7), 1375-1383.

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