Mandy Jackson
Senior Lecturer
INTEGRATIVE PHYSIOLOGY
The University of Edinburgh
United Kingdom
Biography
2013 - present: Senior Lecturer, University of Edinburgh 2010 - 2013: Lecturer, University of Edinburgh 2005 – 2010: RCUK Fellowship in Neuroscience, University of Edinburgh 2002 – 2005: Caledonian Research Fellowship, University of Edinburgh 1998- 2001: Postdoctoral Research Fellow, Johns Hopkins University 1994 – 1997: DPhil, Institute of Molecular Medicine, University of Oxford 1990 – 1994: BSc (Hons) Molecular Biology, University of Edinburgh
Research Interest
Neuroscience
Publications
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Wishart TM, Rooney TM, Lamont DJ, Wright AK, Morton AJ, Jackson M, Freeman MR, Gillingwater TH. (2012) Combining comparative proteomics and molecular genetics uncovers regulators of synaptic and axonal stability and degeneration in vivo. PLoS Genet. 8(8):e1002936.
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Smillie KJ, Pawson J, Perkins EM, Jackson M, Cousin MA. (2013) Control of synaptic vesicle endocytosis by an extracellular signalling molecule. Nat Commun. 4:2394.
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Clarkson YL, Perkins EM, Cairncross CJ, Lyndon AR, Skehel PA, Jackson M. (2014) β-III spectrin underpins ankyrin R function in Purkinje cell dendritic trees: protein complex critical for sodium channel activity is impaired by SCA5-associated mutations. Hum Mol Genet. 23(14):3875-82
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Schnekenberg RP, Perkins EM, Miller J, Davies WIL, D’Adamo MC, Pessia M, Fawcett K, Sims D, Gillard E, Hudspith K, Williams J, O’Regan M, Jayawant S, Jefferson R, Hughes S, Steinlin M, Lustenberger A, Ragoussis J, Jackson M, Tucker ST, Németh AH (2015). De novo point mutations in patients diagnosed with ataxic cerebral palsy. Brain, 138:1817-1832
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Perkins EM, Suminaite D, Jackson M (2016). Cerebellar ataxias: β- III spectrin’s interactions suggest common pathogenic mechanisms. J Physiol., 594:4661-76 [Editor’s choice & front cover image]
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Perkins EM, Suminaite D, Jackson M (2016). Cerebellar ataxias: β- III spectrin’s interactions suggest common pathogenic mechanisms. J Physiol., 594:4661-76 [Editor’s choice & front cover image]
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Perkins EM, Suminaite D, Clarkson YL, Lee SK, Lyndon AR, Wyllie DJA, Rothstein JD, Tanaka K & Jackson M (2016). Posterior cerebellar Purkinje cells in an SCA5/SPARCA1 mouse model are especially vulnerable to the synergistic effect of loss of β-III spectrin and GLAST Hum. Mol. Genet. [Epub ahead of print]
