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Biochemistry Experts

Peter Flatman

Senior Lecturer
Physiology
The University of Edinburgh
United Kingdom

Biography

1980-present: Lecturer, then Senior Lecturer, The University of Edinburgh 1977-80: MRC Research Assistant, Cambridge University 1974-75: Michael Foster Student, Cambridge University 1974-77: MRC Research Student, Cambridge University MA PhD Cambridge University

Research Interest

Roles of magnesium and protein phosphorylation in regulating transport by the sodium pump

Publications

  • Hannemann A, Christie JK & Flatman PW (2009). Functional Expression of the Na-K-2Cl Cotransporter NKCC2 in Mammalian Cells Fails to Confirm the Dominant-negative Effect of the AF Splice Variant. Journal of Biological Chemistry 284, 35348-35358.

  • Hannemann A & Flatman PW (2011). Phosphorylation and Transport in the Na-K-2Cl Cotransporters, NKCC1 and NKCC2A, Compared in HEK-293 Cells. PLoS ONE 6, e17992.

  • Ashek, A., Menzies, R. I., Mullins, L. J., Bellamy, C. O. C., Harmar, A. J., Kenyon, C. J., Flatman, P. W., Mullins, J. J., & Bailey, M. A. (2012). Activation of Thiazide-Sensitive Co-Transport by Angiotensin II in the cyp1a1-Ren2 Hypertensive Rat. PLoS ONE 7, e36311.

  • Hunter RW, Ivy JR, Flatman PW, Kenyon CJ, Craigie E, Mullins LJ, Bailey MA & Mullins JJ. (2015). Hypertrophy in the Distal Convoluted Tubule of an 11β-Hydroxysteroid Dehydrogenase Type 2 Knockout Model. Journal of the American Society of Nephrology 26, 1537-1548.

  • Heye A. K., Thrippleton M. J., Chappell F. M., Valdés Hernández M. dC., Armitage P. A., Makin S. D., Muñoz Maniega S., Sakka E., Flatman P. W., Dennis M. S. & Wardlaw J. M. (2016). Blood pressure and sodium: Association with MRI markers in cerebral small vessel disease. Journal of Cerebral Blood Flow and Metabolism 36, 264-274.

  • Ivy J. R., Oosthuyzen W., Peltz T. S., Howarth A. R., Hunter R. W., Dhaun N., Al-Dujaili E. A. S., Webb D. J., Dear J. W., Flatman P. W. & Bailey M. A. (2016). Glucocorticoids Induce Nondipping Blood Pressure by Activating the Thiazide-Sensitive Cotransporter. Hypertension 67, 1029-1037.

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