Simon Talbot
Senior Lecturer
INFECTION AND PATHWAY MEDICINE
The University of Edinburgh
United Kingdom
Biography
Dr Simon Talbot is a Principal Investigator and Senior Lecturer and his Research Focus To to develop novel antibodies and chimeric T-cell receptors for use in immunotherapy to treat virus induced malignancies and virus infected cells.
Research Interest
T-cell immunotherapy Engineering T-cells to target EBV induced malignancies Engineering T-cells to target Influenza virus
Publications
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Douglas, J., Dutia, B., Rhind, S., Stewart, J.P. & Talbot, S. J. (2004) Journal of Virology 78(16), 8878-8884. Expression in a recombinant murid herpesvirus 4 reveals the in vivo transforming potential of the K1 open reading frame of Kaposi’s sarcoma associated herpesvirus.
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Talbot, S. J. & Crawford, D. H. (2009) Viruses and Cancer. In Medicine 2009: 37:10, 541-544
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Brass, A., Douglas, J., Rhind, S., Dutia, B. & Talbot, S. J. (2010) In preparation. Expression of the Kaposi’s sarcoma associated herpesvirus (KSHV) vOx2 protein in a recombinant murid herpesvirus-4: Modulation of the inflammatory response during primary infection in the lung.
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Hindley, C. & Talbot, S. J. (2010) In preparation. Identification of proteins unr and DAP5 interacting with the KSHV vFLIP IRES.
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Bieleski, L. & Talbot, S. J. (2010) In preparation. KSHV orf64 tegument protein is an RNA binding nuclear shuttling protein that associates with ND10 domains.
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McAulay K., Timpson A., Schooten E., Debets R., Willemsen R., Johannessen I., Crawford D.H. and Talbot S.J. (2010) In preparation. A Chimaeric T-cell receptor targeting an external loop of the EBV Latent membrane protein-1 directs specific killing of EBV transformed cells
