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William G Hill

Professor
BIOLOGICAL SCIENCES
The University of Edinburgh
United Kingdom

Biography

Professor William G Hill teaches Quantitative Genetics and his Research grouping is Population Genetics, Animal Breeding

Research Interest

Animal breeding and maintains variation in complex traits within populations, both the genetic and the environmental components, and in particular the role of mutations. Thus we are developing theory aimed at explaining levels of, for example, heritability, and in considering breeding programmes which influence the homogeneity of livestock products.

Publications

  • Hill, W.G. 2000. Maintenance of quantitative genetic variation in animal breeding programmes. Livest. Prod. Sci. 63: 99-109.

  • Thomas, S.C. and Hill, W.G. 2000. Estimating quantitative genetic parameters using sibships reconstructed from marker data. Genetics 155: 1961-1972.

  • Weir, B.S. and Hill, W.G. 2002. Estimating F-statistics. Ann. Rev. Genet. 36:721-750.

  • Zhang, X.-S., Wang. J. and Hill, W.G. 2004 .Influence of dominance, leptokurtosis and pleiotropy of deleterious mutations on quantitative genetic variation at mutation-selection balance. Genetics 166: 597-610.

  • Zhang, X.-S. and Hill, W.G. 2005. Evolution of the environmental component of the phenotypic variance: stabilizing selection in changing environments and the cost of homogeneity. Evolution 59: 1237-1244.

  • Weir, B.S., Cardon, L.R., Anderson, A.D., Nielsen, D.M. and Hill, W.G. 2005. Measures of human population structure show heterogeneity among genomic regions. Genome Res. 15: 1468-1476

  • Rowe, S.J., White, I.M.S., Avendano, S. and Hill, W.G. 2006. Genetic heterogeneity of residual variance in broiler chickens. Genet. Sel. Evol. 38: 617-635.

  • Mulder, H.A., Bijma, P. and Hill, W.G. 2007. Prediction of breeding values and selection responses with genetic heterogeneity of environmental variance. Genetics 175: 1895-1910.

  • Hill, W.G. and Hernandez-Sanchez, J. 2007. Prediction of multi-locus identity-by-descent. Genetics 176: 2307-2315.

  • Hill, W.G., Goddard, M.E. and Visscher, P.M. 2008. Data and theory point to mainly additive genetic variance for complex traits. PLoS Genetics (in press).

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