Alex Conradie
Chemical and Environmental Engineering
The University of Nottingham
United Kingdom
Biography
Alex graduated with a BEng (Hons) in chemical engineering from Stellenbosch University in 1995 followed by two formative years working in the industrial gases sector as a production engineer. Having established a firm interest in process control and the associated economic benefits, he returned to Stellenbosch University, completing an MSc and a PhD in chemical engineering with a focus on non-linear process control. During his PhD, Alex was a visiting researcher at the University of Texas at Austin within Computer Science, fostering an abiding interest in optimisation methodologies. Given the challenges presented by the non-linear dynamics associated with bioreactors, Alex returned to industry within the biotechnology sector. He was responsible for the R&D, scale-up and technology transfer for a number of new amino acid production technologies with a particular focus on fermentation cultivation strategies and continuous adsorption processes. Moving to the UK, Alex gained expertise in the biologics sector within senior technical and programme management leadership roles. Returning to industrial biotechnology, Alex led as primary inventor in the creation of the technology platform within a polymer manufacturer's Sustainability Group, geared towards polyamide monomer and alkene production. He spearheaded the establishment of a world-class gas fermentation laboratory and systems biology capability. In the interface between science and engineering, he filled a pivotal role as technology integrator covering process conceptualisation, techno-economic analysis, scale-up, process modelling and process design; collaborating with centres of excellence within the UK, USA and Europe.
Research Interest
Collaborating with colleagues across departments, Alex' principal research interests lie in: C1 feedstock exploitation in biochemical processes, optimising mass transfer in novel reactor designs Sustainable development, connecting industrial and agricultural waste streams to value-adding products Synergistic integration between biochemical and chemical conversion Creation of carbon efficient non-natural biochemical pathways towards value-adding products Economic downstream process development, particularly incorporating continuous adsorption and crystallisation unit operations Metabolic engineering, leveraging systems biology Spectroscopy-enabled bioreactor process control
Publications
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BOTES AL, VAN ECA, HADDOUCHE R. Methods, reagents and cells for biosynthesizing compounds. (2015).
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BOTES AL, VAN CA. Methods for biosynthesis of isoprene. (2015).
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BOTES AL, VAN EC, HADDOUCHE R. Methods of producing 6-carbon monomers from 8-carbon compounds. (2016).
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BOTES AL, VAN ECA. Methods, reagents and cells for biosynthesizing compound. (2016).