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Biochemistry Experts

Alexey Ruzov


Division of Cancer and Stem Cells
The University of Nottingham
United Kingdom

Biography

Education 2000 Institute of Gene Biology, Russian Academy of Sciences, Moscow Ph.D. in Molecular Genetics entitled "Transcriptional regulation of tag7/PGRP gene in different model systems." 1996 Lomonosov's Moscow State University, Biological Faculty Department of Bioorganic Chemistry. MSc in Biochemistry. Honours diploma.   Career Feb 2011 - Present time: Lecturer in Stem Cell Biology, Wolfson Centre for Stem Cells, Tissue Engineering and Modelling (STEM), Centre for Biomolecular Sciences, University of Nottingham, Nottingham, UK. Feb 2009 - Jan 2011: Research Fellow, Scottish Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK. Jul 2008 - Jul 2009: Research Fellow, Institute of Genetics and Molecular Medicine (IGMM), Cancer Research Centre, Edinburgh, UK. Jun 2004 - Apr 2008: Carrier Development Fellow, IGMM, Medical Research Council Human Genetics Unit (MRC HGU), Edinburgh, UK. Feb 2001 - Aug 2003: Wellcome Trust Travelling Research Fellow, Dept. of Biomedical Sciences, University of Edinburgh, UK. Working with Dr. Richard Meehan on "The role of methyl-CpG binding protein Kaiso in Xenopus development".. Mar 1998 - Aug 1998: Recipient of short-term fellowship, ICGEB, Trieste, Italy. Mar 1998 - May 2000: Ph.D. student, Group of Transcriptional Control and Oncogenesis, Institute of Gene Biology, Moscow, Russia  

Research Interest

Molecular biology techniques, DNA-protein interactions techniques, cell biology techniques,

Publications

  • CICCONE NA, MWANGI W, RUZOV A, SMITH LP, BUTTER C, NAIR V. A B-cell targeting virus disrupts potentially protective genomic methylation patterns in lymphoid tissue by increasing global 5-hydroxymethylcytosine levels. Veterinary research. 45, 108 .(2014).

  • ABAKIR A, WHELDON L, JOHNSON AD, LAURENT P, RUZOV A. Detection of Modified Forms of Cytosine Using Sensitive Immunohistochemistry. Journal of visualized experiments : JoVE. (2016).

  • RAMSAWHOOK A, LEWIS L, COYLE B, RUZOV A. Medulloblastoma and ependymoma cells display increased levels of 5-carboxylcytosine and elevated TET1 expression. Clinical epigenetics. 9, 18 .(2017).

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