Adrian Mulholland
Professor
Department of Chemistry
University of Bristol
United Kingdom
Biography
Adrian Mulholland is Professor in Department of Chemistry in University of Bristol, United Kingdom.
Research Interest
Research interest Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase’.
Publications
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Ranaghan, K, Mulholland, A & Kamp, MVd, 2018, ‘Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase’. ACS Catalysis., pp. 6268-6282
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Hinchliffe, P, Yang, Q, Portal, E, Young, T, Li, H, Tooke, C, Carvalho, MMd, Paterson, N, Brem, J, Ritivirool, P, Tansawai, U, Lei, L, Li, M, Shen, Z, Wang, Y, Schofield, C, Mulholland, A, Shen, J, Walsh, T, Fey, N & Spencer, J, 2017, ‘Insights into the Mechanistic Basis of Plasmid-Mediated Colistin Resistance from the Crystal Structure of the Catalytic Domain of MCR-1’. Scientific Reports, vol 7.
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Beker, WL, Kamp, MWVd, Mulholland, AJ & Sokalski, WA, 2017, ‘Rapid estimation of catalytic efficiency by cumulative atomic multipole moments: application to ketosteroid isomerase mutants’. Journal of Chemical Theory and Computation, vol 13., pp. 945-955
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Watkins, DW, Jenkins, JMX, Grayson, KJ, Wood, N, Steventon, JW, Le Vay, KK, Goodwin, MI, Mullen, AS, Bailey, HJ, Crump, MP, MacMillan, F, Mulholland, AJ, Cameron, G, Sessions, RB, Mann, S & Anderson, JLR, 2017, ‘Construction and in vivo assembly of a catalytically proficient and hyperthermostable de novo enzyme’. Nature Communications, vol 8., pp. 358