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Gary Barker

Lecturer
Department of Biological Sciences
University of Bristol
United Kingdom

Biography

Gary Barker is Lecturer in Department of Biological Sciences,university of Bristol, United Kingdom. He currently have an EU-funded project to investigate micro-fouling of marine surfaces in which we are using high throughput sequencing for the identification of both taxa and genes associated with different anti-fouling compounds. He is also collaborating on projects using the similar techniques to study the microbial colonisation of retreating glacial fore-fields (in collaboration with Alex Anesio) and of humans who have received a nasal flu vaccine (in collaboration with Adam Finn).  He is also working with Juliet Brodie at the Natural History Museum and Chris Yesson at the Institute of Zoology to develop genotyping by sequencing and novel sonar-based survey methods for UK kelps. He currently have a PhD vacancy funded by the EU to develop bioinformatics approaches to mine novel genes from cold environments.

Research Interest

His research interests involve the application of bioinformatics to environmental genomics and crop Single Nucleotide Polymorphism (SNP) datasets.  His interest in environmental genomics dates back to my PhD and postdoctoral work on gene flow in algae and cyanobacteria. In recent years He worked in collaboration with Keith Edwards group at Bristol to generate useful SNP markers for hexaploid bread wheat. He developed pipelines to mine inter-varietal SNPs from exome-capture sequence data and we went on to develop two commercial genotyping arrays from the ~1 million putative SNPs we found. These arrays are now used extensively by UK wheat breeders to rapidly screen new breeding lines at an early stage for markers linked to useful traits such as disease resistance and their impact has been to drastically reduce the time taken to naturally breed new wheat varieties. The advent of Next Generation Sequencing technology for DNA has made population-scale analysis of microbial communities tractable in recent years, which has enabled me to re-visit this area of my research

Publications

  • Wilkinson, PA, Winfield, MO, Barker, GLA, Tyrrell, S, Bian, X, Przewieslik-Allen, S, Burridge, A, Coghill, J, Waterfall, C, Caccamo, M, Davey, R & Edwards, K, 2016, ‘CerealsDB 3.0: Expansion of resources and data integration’. BMC Bioinformatics, vol 17.

  • Bradley, J, Arndt, S, Sabacka, M, Benning, L, Barker, G, Blacker, J, Yallop, M, Wright, K, Bellas, C, Telling, J, Tranter, M & Anesio, A, 2016, ‘Microbial dynamics in a High Arctic glacier forefield: a combined field, laboratory, and modelling approach’. Biogeosciences, vol 13., pp. 5677-5696

  • Allen, AM, Winfield, MO, Burridge, AJ, Downie, RC, Benbow, HL, Barker, GLA, Wilkinson, PA, Coghill, JA, Waterfall, CM, Davassi, A, Scopes, G, Pirani, A, Webster, T, Brew, F, Bloor, C, Griffiths, S, Bentley, A, Alda, M, Jack, P, Phillips, AL & Edwards, KJ, 2017, ‘Characterisation of a Wheat Breeders’ Array suitable for high throughput SNP genotyping of global accessions of hexaploid bread wheat (Triticum aestivium)’. Plant Biotechnology Journal, vol 15., pp. 390?401

  • Winfield MO, Allen AM, Wilkinson PA, Burridge AJ, Barker GL, Coghill J, Waterfall C, Wingen LU, Griffiths S, Edwards KJ. High density genotyping of the AE Watkins Collection of hexaploid landraces identifies a large molecular diversity compared to elite bread wheat. Plant Biotechnology Journal. 2017 May 13.

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