Lieve Desbonnet
Lecturer
Department of Life Sciences
University of Glasgow
United Kingdom
Biography
Dr Lieve Desbonnet is currently working as a Lecturer in the Department of Life Sciences
Research Interest
Neurodevelopmental disorders and the impact environmental factors (stress, infection, perturbations of the gut microbiota) experienced during early life have on brain development and behaviour, particularly social and cognitive behaviours. The interplay between these environmental factors and identified risk genes, and the mechanisms by which gene-environment interactions alter the trajectory of brain development to increase the risk for schizophrenia and autism.
Publications
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Golubeva, A. V. et al. (2015) Prenatal stress-induced alterations in major physiological systems correlate with gut microbiota composition in adulthood. Psychoneuroendocrinology, 60, pp. 58-74.
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O'Tuathaigh, C. M.P. et al. (2017) Epistatic and independent effects on schizophrenia-related phenotypes following co-disruption of the risk factors Neuregulin-1 × DISC1. Schizophrenia Bulletin, 43(1), pp. 214-225.
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Desbonnet, L., Cox, R., Tighe, O., Lai, D., Harvey, R. P., Waddington, J. L. and O'Tuathaigh, C. M.P. (2017) Altered cytokine profile, pain sensitivity, and stress responsivity in mice with co-disruption of the developmental genes Neuregulin-1 × DISC1. Behavioural Brain Research, 320, pp. 113-118.
