Peter Adams
Professor
Epigenetics
University of Glasgow
United Kingdom
Biography
Adam investigates the impact of chromatin structure and epigenetics on cell proliferation, aging and cancer. In particular, we hypothesize that age-associated changes in chromatin structure, function and regulation contribute to the dramatic age-associated increase in incidence of cancer.
Research Interest
DNA methylation, age-associated changes in chromatin structure, function and regulation contribute to the dramatic age-associated increase in incidence of canceR, Epigenetics.
Publications
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Wang, T., Tsui, B., Kreisberg, J. F., Robertson, N. A., Gross, A. M., Yu, M. K., Carter, H., Brown-Borg, H. M., Adams, P. D. and Ideker, T. (2017) Epigenetic aging signatures in mice livers are slowed by dwarfism, calorie restriction and rapamycin treatment. Genome Biology, 18, 57.
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Cole, J. J. et al. (2017) Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions. Genome Biology, 18, 58.
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Leung, E.Y., McMahon, J.D., McLellan, D., Syyed, N., McCarthy, C.E., Nixon, C., Orange, C., Brock, C., Hunter, K. and Adams, P.D. (2017) DNA damage marker histone H2AX is a potential predictive marker for progression of epithelial dysplasia of the oral cavity.
