Richard Burchmore

Biography

Richard Burchmore is currently working as a Senior Lecturer in the Department of Infection, Immunity & Inflammation

Research Interest

Understanding, at the molecular level, the mechanisms by which parasites thrive in the challenging environments which they encounter. Complex phenotypes such as drug resistance and virulence are of central relevance in parasitology and are amenable to global approaches such as proteomics and metabolomics. In recent years I have brought these new technologies to bear upon the systems biology of parasites and of host:parasite interactions. In parallel, I have applied more conventional reverse genetic and biochemical approaches to specifically perturb parasite systems and to validate the results of proteomic analyses. My primary parasite of interest is Leishmania, but I have also worked extensively with trypanosomes. Through collaborative links with other parasitologists, I have applied proteomic approaches to a diverse range of parasites, as well as to other biological systems. Current areas of research focus include understanding the role of nutrient transporters and stress responses in parasite development, virulence and drug resistance.