Simon Milling
Professor
Department of Infection, Immunity & Inflammation
University of Glasgow
United Kingdom
Biography
Simon Milling is currently working as a Professor in the Department of Infection, Immunity & Inflammatio
Research Interest
Biology of dendritic cells in the intestine, and on how these cells respond to infectious or inflammatory stimuli. We study the functions of dendritic cell subsets in vivo, using samples from mice and from people. The aim of this work is to understand the vital roles that dendritic cells play, both in the induction and polarisation of adaptive immune responses against pathogens, and in the pathology of inflammatory diseases. We hope to use this information to manipulate the immune response, either to generate improved strategies for vaccination, or to inhibit inflammatory pathology.
Publications
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Kurowska-Stolarska, M. et al. (2017) MicroRNA-34a dependent regulation of AXL controls the activation of dendritic cells in inflammatory arthritis. Nature Communications, 8, 15877.
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Giampazolias, E. et al. (2017) Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency. Nature Cell Biology, 19(9), pp. 1116-1129.
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Ansalone, C., Utriainen, L., Milling, S. and Goodyear, C. S. (2017) Role of gut inflammation in altering the monocyte compartment and its osteoclastogenic potential in HLA-B27-transgenic rats. Arthritis and Rheumatology, 69(9), pp. 1807-1815.
