Roger Phillips
Professor
Marine Biology and Biochemistry
University of Huddersfield
United Kingdom
Biography
Following a BSc in Marine Biology and Biochemistry (Joint Honours) from University College of North Wales, Bangor, Roger specialised in Cancer Pharmacology gaining his PhD in 1988 from the University of Bradford (under Profs John Double and Mike Bibby). After an initial postdoctoral position in Bradford, he moved to the School of Pharmacy, University of Southern California, Los Angeles to work with Dr Neil Gibson in 1991. He returned to Bradford in 1993 and secured academic appointments as lecturer (1996 to 2001), Senior Lecturer (2001 to 2003) and Reader (2003 to 1014) in Cancer Pharmacology. In July 2014, Roger was appointed as Professor of Cancer Pharmacology at the University of Huddersfield. He was also appointed as Director of Research in the School of Applied Sciences in August 2015. His research focuses on the preclinical and early clinical evaluation of novel anti-cancer drugs with a specific interest in the tumour microenvironment as a target for drug development. His research has had clinical impact through the development of EO9 as a therapeutic drug for the treatment of superficial bladder cancer. He has published extensively in internationally recognised journals, has successfully supervised over 20 PhD students and continues to present his work at national and international conferences. He is a committee member of the European Organisation for the Research and Treatment of Cancer (EORTC) Drug Development Committee and the Pharmacology and Molecular Mechanism Group. He is also an editorial board member for the British Journal of Pharmacology.
Research Interest
His current research interests include: Preclinical development of novel anti-cancer drugs Phenotype based screening Development of experimental models that reflect the complexity of tumour biology The hypoxic tumour microenvironment as a target for drug development Drug delivery to hypoxic regions of solid tumours
Publications
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Hubbard, M., Jove, M., Loadman, P., Phillips, R., Twelves, C. and Smye, S. (2017) ‘Drug delivery in a tumour cord model: a computational simulation’ Royal Society Open Science . ISSN 2054-5703
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Allison, S., Sadiq, M., Baronou, E., Cooper, P., Dunnill, C., Georgopoulos, N., Latif, A., Shepherd, S., Shnyder, S., Stratford, I., Wheelhouse, R., Willans, C. and Phillips, R. (2017) ‘Preclinical anti-cancer activity and multiple mechanisms of action of a cationic silver complex bearing N-heterocyclic carbene ligands’ Cancer Letters . ISSN 0304-3835
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Phillips, R., Hendriks, H., Sweeney, J., Reddy, G. and Peters, G. (2017) ‘Efficacy, pharmacokinetic and pharmacodynamic evaluation of Apaziquone in the treatment of non- muscle invasive bladder cancer’ Expert Opinion on Drug Metabolism & Toxicology . ISSN 1742-5255