Genetics
Global

Genetics Experts

Flaviano Giorgini

Professor
Department of Genetics and Genome Biology
University of Leicester
United Kingdom

Biography

BSc (West Lafayette) MA (St. Louis) PhD (Seattle) I grew up amidst the corn fields of Indiana and pursued a BSc degree in Biological Sciences (with an emphasis in Genetics) at Purdue University. I obtained a MA degree in Molecular Genetics at Washington University in Saint Louis and a PhD in Genetics at the University of Washington in Seattle.

Research Interest

Huntington's disease (HD) is a fatal neurodegenerative disorder inherited in an autosomal dominant manner. This disease is caused by an expansion of a polyglutamine tract in the protein huntington and is characterised by atrophy in the striatum and cortex of the brain. The most common symptomatic manifestations of the disease are chorea (involuntary jerking of muscles), cognitive deficits and psychiatric disturbances. Although the initiating trigger in HD is known, the critical molecular mechanisms underlying this devastating illness remain unresolved. Our work focuses on elucidating these molecular mechanisms with the hope of aiding in the development of therapeutic strategies for HD.

Publications

  • Herrera F, Po├žas GM, Pires-Afonso Y, Giorgini F, Domingos PM, et al., (2017). Protein phosphatase 1 regulates huntingtin exon 1 aggregation and toxicity. 26(19):3763-3775.

Global Experts from United Kingdom

Global Experts in Subject

Share This Profile
Recommended Conferences
  • 12th Annual Conference on Stem Cell and Regenerative Medicine

    June 04-06, 2018 Prague, Czech Republic

  • 13th International Conference on Tissue Engineering and Regenerative Medicine

    July 12-13, 2018 Paris, France

  • World Congress on Stem Cell Biology and Biobanking

    September 3-4, 2018 Tokyo, Japan

  • 11th International Conference on Genomics and Pharmacogenomics September 21-22, 2018 Philadelphia, Pennsylvania, USA

    September 21-22, 2018 Philadelphia, USA

  • 5th International Conference on Human Genetics and Genetic Disorders September 21-22,2018 Philadelphia, Pennsylvania, USA

    September 21-22,2018 Philadelphia, USA

  • 11th International Conference on Genomics and Pharmacogenomics

    September 21-22, 2018 Philadelphia, USA

  • 5th World Congress on HUMAN GENETICS SEPTEMBER 24-25, 2018 BERLIN, GERMANY

    SEPTEMBER 24-25, 2018 Berlin, Germany

  • Next Generation Sequencing and Biostatistics

    Oct 23-24, 2018 Dubai

View more