Neurology Experts

Irene Gottlob

Department of Neuroscience
University of Leicester
United Kingdom


I lead the Leicester Ophthalmology group and my main areas of research are the regulation of eye movements and their disorders, in particular nystagmus. Current areas of active research include understanding the genetics of neuro-ophthalmic diseases, improving diagnosis and treatment of nystagmus, amblyopia and other neuro-ophthalmic diseases.

Research Interest

Nystagmus Infantile nystagmus (IN) is a to and fro oscillation of the eyes which is estimated to have a prevalence of 2.4 per 1000. It has a direct impact upon visual function through constant motion of images on the retina as well as often being associated with retinal deficits. IN also has a profound effect on psychosocial aspects of life such as self-esteem and confidence. More than a decade of collaborative research has resulted in the Leicester group being at the forefront of nystagmus research pioneering investigations from many different aspects the disease.


  • Betts-Henderson J, Bartesaghi S, Crosier M, Lindsay S, Chen HL, Salomoni P, Gottlob I, Nicotera P. The nystagmus-associated FRMD7 gene regulates neuronal outgrowth and development. Hum Mol Genet. 2010 Jan 15;19(2):342-51.

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